Sunday, September 23, 2012

Jaripeo de Lujo at the Central Washington State Fair September 23, 2012

Jaripeo de Lujo at the Central Washington State Fair

9/23/2012

Event submitted by: State Fair Park

Location: Yakima
1301 S Fair Ave On opening Sunday, September 23, the Jaripeo de Lujo will be the featured
entertainment at the Grandstand.? The event will include several different Mexican musicians and some bull riding in one big show starting at 2 p.m. For tickets call 1-800-325-SEAT or visit the website at www.fairfun.com.

View other events submitted by State Fair Park

Source: http://visityakima.com/newSite/yakima-valley-event-detail.asp?eventID=5523

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How to Sharpen Nail Clippers [Sharpening]

How to Sharpen Nail ClippersIf your nail clippers don't clip as cleanly as they once did you can always toss them and buy another pair, but if you have a nice manicure set you may prefer to instead sharpen them and bring back to their prime.

Instructables user Phil B shares that the easiest way to sharpen convex clippers is to remove the actuating lever, screw the jaws together with a screw and nut, and sharepen the jaws of the clipper on a flat sharpening stone. If you have concave jaws on your clippers you'll want to instead cover a dowel with sandpaper and use that as a sanding drum.

Full details and photos can be found at the source link below.

Sharpen a Nail Clipper | Instructables

Source: http://feeds.gawker.com/~r/lifehacker/full/~3/jW4f_SwG2gg/how-to-sharpen-nail-clippers

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Latest developments in protest of anti-Islam film

Here's a look at protests and events across the world on Friday connected to an amateurish anti-Muslim film produced in the United States and vulgar caricatures of the Prophet Muhammad published in a French satirical weekly. More than 47 people, including the U.S. ambassador to Libya, have been killed in violence linked to the protests over the film, which has also renewed debate over freedom of expression in the U.S. and in Europe.

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PAKISTAN

Seventeen people were killed and dozens were injured as tens of thousands protested against the film around the country after the government encouraged peaceful protests and declared a national holiday ? "Love for the Prophet Day." Demonstrations turned violent in several Pakistani cities. Among those killed was a driver for a Pakistani television station, who died after police opened fire on rioters torching a cinema in the northwest city of Peshawar during a protest.

Clashes between police and thousands of stone-throwing protesters also occurred in Lahore, Karachi and Islamabad, the Pakistani capital.

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AFGHANISTAN

About 900 people have gathered for a protest against the film in the capital, Kabul, chanting "death to America" and burning an effigy of President Barack Obama and an American flag. A few hundred demonstrators also protested inside a mosque in the eastern city of Ghazni. The protests were peaceful.

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IRAN

Iranian President Mahmoud Ahmadinejad lashed out at the West over the film. Speaking during a military parade in Tehran, he said: "in return for (allowing) the ugliest insults to the divine messenger, they ? the West ? raise the slogan of respect for freedom of speech." He said this explanation was "clearly a deception."

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INDONESIA

The United States closed its diplomatic missions across Indonesia due to continuing demonstrations over the anti-Islam film. Small and mostly orderly protests were held outside the U.S. Embassy in Jakarta and in the cities of Surabaya and Medan, along with a couple other smaller towns. No violence was reported.

In addition to the embassy in Jakarta and consulate offices in Surabaya, Medan and Bali, the American mission to the Association of Southeast Asian Nations also was shut.

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IRAQ

About 3,000 people, mostly followers of Iranian-backed Shiite Muslim groups, protested against the film and caricatures in the southern city of Basra. Demonstrators carried Iraqi flags and posters of Iran's Supreme Leader Ayatollah Khamenei, chanting "death to America" and "no to America."

They burnt Israeli and American flags. One of the organizers, Qassim al-Moussawi, told AP that people gathered "to express our anger and resentment on the offenses made against our prophet."

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SRI LANKA

About 2,000 Muslims burned effigies of President Barack Obama and American flags at a protest after Friday prayers in the capital, Colombo, demanding that the United States ban the film.

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BANGLADESH

Over 2,000 people marched through the streets of the capital, Dhaka, to protest the film. They burned a makeshift coffin draped in an American flag, and an effigy of Obama.

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LEBANON

Thousands gathered in the Bekaa valley for the latest in a series of protest rallies organized by the Shiite militant group Hezbollah. Protesters carried the yellow Hezbollah flag.

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KASHMIR

Police enforced a daylong curfew in parts of Indian-controlled Kashmir's main city, Srinagar, and chased away protesters opposing the anti-Islam film. Authorities in the region also temporarily blocked mobile phone and Internet services to prevent viewing the film clips.

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GERMANY

Several hundred people gathered in the city of Freiburg in southwest of Germany to protest the film. Some carried banners saying: "The dignity of the Prophet Muhammad is our dignity." Police banned inflammatory slogans.

The Interior Ministry postponed a poster campaign aimed at countering radical Islam among young people due to tensions caused by the online video insulting Islam. Posters for the campaign ? in German, Turkish and Arabic ? were meant to go on display in German cities with large immigrant populations on Friday, but are being withheld because of the changed security situation. Germany is home to an estimated 4 million Muslims.

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NORWAY

Crowds gathered outside the U.S. Embassy in the capital Oslo to protest the prophet film shouting "Obama, Obama, we're all Osama."

Some 70 people took part in the hour-long demonstration on Friday afternoon that lasted about an hour. Police blocked off the street during the peaceful protest.

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PHILIPPINES

A law professor defied a ban by Philippine university officials and has shown students the film's 14-minute trailer. Constitutional law professor Harry Roque of the University of the Philippines said the film was "trash and nothing but trash" and will not convince people Islam is evil.

Source: http://news.yahoo.com/latest-developments-protest-anti-islam-film-183759587.html

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Saturday, September 22, 2012

Facebook shutting down facial recognition in the EU, gets stamp of approval from Ireland DPC

Earlier this year, Ireland's Data Protection Commissioner, a body whose decisions impact Facebook's policies in Europe at large, made several recommendations to bring the website in line with regional privacy laws, calling for greater transparency on how users' data is handled and more user control over settings, among other things. The DPC just officially announced that Zuckerberg et al. have for the most part adjusted its policies accordingly. The biggest change involves the facial recognition feature, which attempts to identify Facebook friends in photos and suggest their names for tagging. The social network turned off this functionality for new users in the EU -- and it will be shutting it down entirely by October 15th. It's not like Ireland, home to Facebook's European HQ, is the first to give the site flack about such features: Germany was having none of it when the site introduced facial recognition last summer.

Continue reading Facebook shutting down facial recognition in the EU, gets stamp of approval from Ireland DPC

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Facebook shutting down facial recognition in the EU, gets stamp of approval from Ireland DPC originally appeared on Engadget on Fri, 21 Sep 2012 10:16:00 EDT. Please see our terms for use of feeds.

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Source: http://www.engadget.com/2012/09/21/facebook-shutting-down-facial-recognition-eu/

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Friday, September 21, 2012

Double assault on tough types of leukemias

Friday, September 21, 2012

Investigators at Northwestern University Feinberg School of Medicine have identified two promising therapies to treat patients with acute megakaryocytic leukemia (AMKL), a rare form of leukemia where the number of cases is expected to increase with the aging population.

The disease is characterized by an overload of white blood cells that remain forever young because they can't mature into specialized cells. Published in a recent issue of the journal Cell, the study found that the drug with the generic name alisertib (MLN8237), induced division and growth of healthy cells to overtake the proliferation or "blasts" of immature cells.

In the study, a mouse model with this leukemia that was treated with alisertib showed a striking reduction in the number of leukemia cells, including dramatic reductions in overwhelming white cell counts and the weights of their spleens and livers, which are indications of leukemia.

Alisertib has been tested before in humans with limited success to treat other types of leukemia and lymphoma, a cancer of the immune system. However, the drug should be effective against AKML in humans because it specifically targets the enzyme Aurora A kinase, said study senior author John Crispino, the Robert I. Lurie, MD, and Lora S. Lurie Professor of Hematology/Oncology at Feinberg. In normal cell development, this enzyme enables healthy cells to proliferate correctly, but with leukemia, is also allows adolescent cells to multiply unchecked if they are in the mix.

Crispino also is a member of the Robert H. Lurie Comprehensive Cancer Center of Northwestern University.

"Alisertib was really potent against the proliferation of cancer cells," Crispino said. "We were incredibly excited when we found that the drug we predict will reverse AMKL is already far along in clinical development. The fact that we don't have to start from scratch means we could be years closer to finding an effective therapy."

Crispino expects alisertib will be a more gentle cancer drug without the ravaging side effects of conventional chemotherapies. This is because the drug specifically targets a key enzyme, avoids healthy cells in the bone marrow and blood, and will probably be more effective at lower doses than drugs tested in previous studies.

"This study has given us a scientific rationale to take this drug to an early phase clinical trial in this very challenging form of leukemia," said Jessica Altman, M.D., assistant professor in hematology/oncology at Feinberg and an oncologist at Northwestern Memorial Hospital. Altman also is a member of the Lurie Cancer Center. Together with other leukemia specialists, she is designing a multi-center clinical trial planned to open in 2013.

Investigators also identified another attack plan for other types of leukemias. Sifting through 9,000 chemical compounds during the study, they found that dimethylfasudil boosted the number of mature bone marrow cells and shot down malignant ones.

Dimethylfasudil could be useful against AMKL and tolerated better by patients, Crispino says. However, he adds that alisertib is moving forward now because there is urgent need and the drug is available. Meanwhile, Crispino's team and other scientists at Northwestern's Center for Molecular Innovation and Drug Discovery are developing the compound dimethylfasudil into an acceptable anticancer drug for clinical trials, which may take two to three years.

Investigators believe dimethylfasudil may be valuable to fight other types of leukemias because it has broad action against other enzymes that let cancer cells reproduce.

###

Northwestern University: http://www.northwestern.edu

Thanks to Northwestern University for this article.

This press release was posted to serve as a topic for discussion. Please comment below. We try our best to only post press releases that are associated with peer reviewed scientific literature. Critical discussions of the research are appreciated. If you need help finding a link to the original article, please contact us on twitter or via e-mail.

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Source: http://www.labspaces.net/123727/Double_assault_on_tough_types_of_leukemias

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PSA: Passbook supported apps now listed in iOS 6 App Store

PSA Passbook supported apps now listed in iOS 6 App Store

Now that iOS 6 has officially landed, Apple has pulled back the veil revealing the first wave of apps to support its new Passbook feature. The initial group of companies to jump on the bandwagon include: Ticketmaster, Live Nation, Lufthansa, MLB.com At Bat, Sephora to Go, Walgreens and Fandango Movies. While this list is a tad bit shorter than we hoped for, it's safe to say that more apps will follow in the not-so-distant future. Want to be the first to know when they arrive? Be sure to keep an eye on the Passbook section of the App Store for the latest updates.

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PSA: Passbook supported apps now listed in iOS 6 App Store originally appeared on Engadget on Thu, 20 Sep 2012 06:02:00 EDT. Please see our terms for use of feeds.

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Source: http://www.engadget.com/2012/09/20/psa-passbook-supported-apps-now-listed-in-ios-6-app-store/

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Thursday, September 20, 2012

Streisand, Minnelli, Franklin sing for Marvin Hamlisch

NEW YORK (Reuters) - Three of America's leading stage performers - Barbra Streisand, Liza Minnelli and Aretha Franklin - paid tribute to Marvin Hamlisch on Tuesday, honoring the late composer for his contributions to Broadway and movies, as well as their personal lives.

The invitation-only tribute for the composer of numerous hit records, movies and musicals such as "A Chorus Line" was held at the New York's Juilliard School for the Arts where Hamlisch studied as a boy after three years earlier displaying at the age of 4 a gift for mimicking music.

Hamlisch died after a brief illness in Los Angeles on August 6 at the age of 68, causing an outpouring of grief from well-known entertainers and fans and prompting Streisand, Hamlisch's friend for the past 45 years, to organize the tribute.

Streisand performed "The Way We Were - one of Hamlisch's best known songs and one of Streisand's biggest hits - in the tribute's finale. She also recalled how they first met in 1963 when Hamlisch was the rehearsal pianist for Streisand's movie "Funny Girl," who would also on occasion fetch the cast coffee.

"Because I didn't drink coffee, he was assigned to get me a chocolate doughnut," Streisand told the laughing audience filled with friends, family and stars including Michael Douglas, Sarah Jessica Parker and lyricists Alan and Marilyn Bergman. "But instead of just one, he always brought me two and so our love affair began."

Streisand told how she forged a friendship with the New York-born composer based on a shared passion for "music, film and food," and "without explaining why or how, we understood each others anxieties," while joking about their shared Jewish heritage.

MINNELLI'S CONSTANT

They ended up with a long history of working together, including Hamlisch's turn as musical director and arranger of Streisand's 1994 U.S. concert tour as well as writing the score for Streisand's 1996 film, "The Mirror Has Two Faces." Hamlisch had called Streisand "the best voice there is."

Earlier Liza Minnelli, who performed "If You Really Knew Me" from Hamlisch's Tony-nominated 1979 musical, "They're Playing Our Song," said she met the composer, "when I was 14 and a half, and he was 15 and three-quarters," and soon became best friends: "He was one of my few constants that I had in my life."

Aretha Franklin sang a rousing version of Hamlisch's power ballad "Nobody Does It Better," which he wrote as the theme song for the 1977 James Bond film "The Spy Who Loved Me." She inserted the lyric, "Marvin, you are the best" to audience cheers before lowering her voice for the spiritual ballad "Deep River."

Other performers included Chinese pianist Lang Lang, British stage singer Maria Friedman and trumpeter Chris Botti who all performed songs from the 1975 musical "A Chorus Line," for which Hamlisch won a Tony award and a Pulitzer Prize and which at the time became the most successful show on Broadway.

Hamlisch worked right up until the days before his death and the tribute showed off one of his more recent songs about his love for life, "While I Still Have The Time," from the Jerry Lewis stage-adapted comedy musical, "The Nutty Professor," which opened this year.

Hamlisch had the rare distinction of winning Emmy, Grammy, Oscar and Tony awards.

His wife, Terre Blair Hamlisch, began the tribute recalling how Hamlisch often said he believed in the power of music to connect people, and Streisand ended it 90 minutes later.

A scholarship program at The Juilliard School was established in Hamlisch's memory.

(Editing by Bill Trott)

Source: http://news.yahoo.com/streisand-minnelli-franklin-sing-marvin-hamlisch-054726494.html

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